服务平台拥有丰富的技术服务经验，一流的仪器设备，先进的检测手段和严格的质量控制体系，力求为全球药物研发机构提供优质高效的技术服务
产品介绍 This assay kit is designed to measure the inhibition of the HSP90α binding to its protein target PPID (also known as Cyclophilin D) in a homogeneous, 96 reaction format. This assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple. A sample containing terbium-labeled donor, dye-labeled acceptor, HSP90α, substrate, and an inhibitor is incubated for 2 hours. The protein-protein interaction is then assayed by measuring the TR-FRET between the PPID and HSP90α using a fluorescence reader.
询价产品介绍 Human induced Heat Shock Protein 70 (Q435A), also known as induced HSP70 and HSP70i, with a Gln to Ala mutation on a.a. 435 of the HSP70 protein. GenBank Accession No. NM_005345, a.a. 1-641(end) with C-terminal His-tag, MW = 70.8 kDa, expressed in an E. coli expression system.
询价背景介绍 In cooperation with other chaperones, Hsp70 stabilizes preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. 产品介绍 Human Heat Shock Protein 70 (GenBank Accession No. NM_005345), a.a. 2-641 with C-terminal His-tag, MW = 71 kDa, expressed in E. coli.
询价背景介绍 Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. Sestrin 2 is involved in cellular response to different stress conditions and is involved in the reduction of peroxiredoxins. 产品介绍 Human Sestrin2, also known as hypoxia induced gene 95 (GenBank Accession No. NM_031459), full length, a.a. 2-480(end), with N-terminal FLAG-tag, MW=55 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
询价产品介绍 Human Heat Shock Protein 40 (GenBank Accession No. NM_006145), full length with C-terminal His-tag, MW = 38.5 kDa, expressed in an E. coli expression system. Reference: Gibbs, S.J., et al. PLoS ONE. 2009;4(2):e4595.
询价背景介绍 Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. Sestrin 1 mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mTOR protein. Sestrin 1 in important for antioxidant defense because it regenerates overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. 产品介绍 Human Sestrin1, also known as p53-regulated protein PA26 (GenBank Accession No. NM_014454), full length, a.a. 2-551(end), with N-terminal FLAG-tag, MW=65 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
询价产品介绍 Human SUZ12 (suppressor of zeste 12), Genbank Accession #NM_015355, (a.a. 2-739 (end)) with N-terminal His and FLAG-tags, MW = 85 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
询价产品介绍 Human Adipocyte Enhancer binding protein 2 (AEBP2), GenBank Accession No. NM_153207, a.a. 2-503 (end) with N-terminal His-tag, MW=53.6 kDa, expressed in Sf9 cells via a baculovirus expression system. Runs at ~70 kDa on SDS-PAGE gels. *Note: Protein runs aberrantly in SDS-PAGE gels, and has been confirmed by Western blotting.
询价产品介绍 Human Embryonic Ectoderm Development (hEED), also known as WAIT-1, GenBank Accession No. NM_003797, a.a. 2-end with N-terminal FLAG-tag, MW= 51 kDa, expressed in Sf9 cells via a baculovirus expression system.
询价
