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产品介绍 Polyclonal antibody raised in rabbit against histone H3 containing the monomethylated lysine 27 (H3K27me1), using a KLH-conjugated synthetic peptide.
询价产品介绍 Polyclonal antibody raised in rabbit against histone H3, acetylated at lysine 27 (H3K27ac), using a KLH-conjugated synthetic peptide.
询价产品介绍 Monoclonal antibody raised in mouse against histone H3 acetylated at lysine 27 (H3K27ac), using a KLH-conjugated synthetic peptide
询价背景介绍 Acetylation of histone H3 is associated with active gene transcription. Acetylation at H3K18 and H3K24 favors methylation at H3R17me by CARM1/PRMT4. SIRT7 is a chromatin-associated H3K18Ac-specific deacetylase. Studies show a significant correlation between low expression of H3K18ac and better prognosis of patients with oesophageal squamous cell carcinoma. 产品介绍 Polyclonal antibody raised in rabbit against histone H3 containing the acetylated lysine 18 (H3K18ac), using a KLH-conjugated synthetic peptide
询价背景介绍 Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histones play a central role in the regulation of transcription, DNA repair, DNA replication and chromosomal stability. These different functions are established via a complex set of post-translational modifications which either directly or indirectly alter chromatin structure and DNA accessibility to facilitate transcriptional activation or repression or other nuclear processes. 产品介绍 Polyclonal antibody raised in rabbit against two KLH-conjugated synthetic peptides containing an unmodified sequence from the central part and from the C-terminus of histone H3, respectively.
询价产品介绍 Monoclonal antibody raised in mouse against histone H2B containing the phosphorylated Serine 14 (H2BS14p), using a KLH-conjugated synthetic peptide.
询价产品介绍 Polyclonal antibody raised in rabbit against the region of histone H2B containing the acetylated lysine 15 (H2BK15ac), using a KLH-conjugated synthetic peptide.
询价产品介绍 Polyclonal antibody raised in rabbit against the region of histone H2B containing the acetylated lysine 12 (H2BK12ac), using a KLH-conjugated synthetic peptide.
询价背景介绍 Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histones play a central role in the regulation of transcription, DNA repair, DNA replication and chromosomal stability. These different functions are established via a complex set of post-translational modifications which either directly or indirectly alter chromatin structure and DNA accessibility to facilitate transcriptional activation or repression or other nuclear processes. 产品介绍 Polyclonal antibody raised in rabbit against histone H2B using a KLH-conjugated synthetic peptide containing an unmodified sequence from the C-terminal part of the protein.
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