服务平台拥有丰富的技术服务经验，一流的仪器设备，先进的检测手段和严格的质量控制体系，力求为全球药物研发机构提供优质高效的技术服务
背景介绍 EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival (1). Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms (2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. 产品介绍 Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with AH insertion between H773 and V774. Genbank Accession NM_005228, a.a. 695 end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 89 kDa.
询价背景介绍 EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival (1). Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms (2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. 产品介绍 Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with G719S mutation. Genbank Accession NM_005228, a.a. 695 end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 89 kDa.
询价背景介绍 EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival (1). Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms (2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. 产品介绍 Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with G719D mutation. Genbank Accession NM_005228, a.a. 695 end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 89 kDa.
询价背景介绍 EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival (1). Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms (2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. 产品介绍 Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with G719C mutation. Genbank Accession NM_005228, a.a. 695 end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 89 kDa.
询价背景介绍 EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival (1). Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms (2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. 产品介绍 Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with NPG insertion between D770 and N771. Genbank Accession NM_005228, a.a. 668- end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 100 kDa.
询价背景介绍 EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival (1). Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms (2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. 产品介绍 Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with GF insertion between D770 and N771. Genbank Accession NM_005228, a.a. 695 end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 87 kDa.
询价背景介绍 EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival (1). Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms (2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. 产品介绍 Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with D770GY mutation. Genbank Accession NM_005228, a.a. 695 end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 89 kDa.
询价背景介绍 EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival (1). Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms (2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. 产品介绍 Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with D761Y mutation. Genbank Accession NM_005228, a.a. 695 end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 89 kDa.
询价背景介绍 EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival (1). Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms (2). Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. 产品介绍 Recombinant Human EGFR also known as ERBB, mENA, ERBB1, and HER1 with 752-759 deletion. Genbank Accession NM_005228, a.a. 695 end, with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 87 kDa.
询价
