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背景介绍 Tau-410 or Tau-C is a member of the Tau family of proteins which function to stabilize the microtubules by binding to them. Tau proteins are subject to phosphorylation and this phenomenon regulates the association of the Tau protein with the microtubules. Deposits of Alzheimer's disease AD-associated proteins, such as hyperphosphorylated Tau, as well as other shared misfolded proteins, such as β-amyloid precursor protein (βAPP), ubiquitin, and various chaperones and protein kinases, are thought to play a pathologic role in the cognitive decline and muscular failure. Malfunctioning of Tau proteins is associated with microtubules disintegration and collapsing of the neuronal transport system. 产品介绍 Human Tau-410 Protein, GenBank Accession No. P10636-5, full length, expressed in an E. coli expression system. MW = 61 kDa.
询价背景介绍 Tau-383 or Tau-D is a member of the Tau family of proteins which function to stabilize the microtubules by binding to them. Tau proteins are subject to phosphorylation and this phenomenon regulates the association of the Tau protein with the microtubules. Deposits of Alzheimer's disease AD-associated proteins, such as hyperphosphorylated Tau, as well as other shared misfolded proteins, such as β-amyloid precursor protein (βAPP), ubiquitin, and various chaperones and protein kinases, are thought to play a pathologic role in the cognitive decline and muscular failure. Malfunctioning of Tau proteins is associated with microtubules disintegration and collapsing of the neuronal transport system. 产品介绍 Human Tau-383 Protein, GenBank Accession No. P10636-6, full length, expressed in an E. coli expression system. MW = 52 kDa.
询价背景介绍 Tau-383 or Tau-D is a member of the Tau family of proteins which function to stabilize the microtubules by binding to them. Tau proteins are subject to phosphorylation and this phenomenon regulates the association of the Tau protein with the microtubules. Deposits of Alzheimer's disease AD-associated proteins, such as hyperphosphorylated Tau, as well as other shared misfolded proteins, such as β-amyloid precursor protein (βAPP), ubiquitin, and various chaperones and protein kinases, are thought to play a pathologic role in the cognitive decline and muscular failure. Malfunctioning of Tau proteins is associated with microtubules disintegration and collapsing of the neuronal transport system. 产品介绍 Human Tau-383 (N352H) Protein, GenBank Accession No. P10636-6, full length, expressed in an E. coli expression system. MW = 51 kDa.
询价背景介绍 Recombinant human FN is a major component of the provisional ECM produced during sprouting angiogenesis. 产品介绍 Human fibronectin 1 (FN1, also known as CD36), Genbank Accession number X02761.1, a.a. 2175 - 2386 with a C-terminal His-tag, expressed in an HEK293 cell expression system. MW =28 kDa. This protein migrates at a higher than expected molecular weight due to glycosylation.
询价产品介绍 Human Calmodulin 1, also known as CALM1, CALML2, CAMI, DD132, PHKD, GenBank Accession No. NM_006888, full-length with an N-terminal His-tag, expressed in an E. coli cell expression system. MW = 17 kDa.
询价背景介绍 While the disubstituted rhodamine moiety in Ub-Rho110-G is essentially non-fluorescent, cleavage results in a mono-substituted rhodamine, Rho110-G, which exhibits intense fluorescence when excited at 485 nm. The longer excitation and emission wavelengths (Ex485 nm, Em535 nm) of the rhodamine fluorophore reduces the risk of artifacts in screens due to autofluorescence, which can make ubiquitin-rhodamine more appropriate than Ubiquitin-AMC for some compound screening and profiling assays. 产品介绍 Ubiquitin-rhodamine 110 is a quenched, fluorescent substrate for deubiquitylases, especially ubiquitin C-terminal hydrolases. Cleavage of the amide bond between the C-terminal glycine of ubiquitin and rhodamine results in an increase in rhodamine fluorescence at 535 nm (Exc. 485 nm).
询价背景介绍 Ubiquitin-AMC is prepared via the conjugation of the C-terminus of mature, Ubiquitin with 7-amino-4-methylcoumarin (AMC). This conjugation quenches the intrinsic fluorescence of AMC. The high purity of BPS's Ubiquitin-AMC compared to that of other commercial vendors leads to a greater signal:background. 产品介绍 Ubiquitin-AMC is a fluorogenic substrate for ubiquitin hydrolases based on the C-terminus derivatization of ubiquitin with 7-amido-4-methylcoumarin (AMC). Upon incubation with a protease recognizing Ubiquitin, such as USP2 or UCHL3, AMC is released and the increase in fluorescence can be measured using Ex380 nm and Em460 nm wavelengths. This protein contains no extraneous tags.
询价背景介绍 Yod1 is the mammalian homolog of the S. cerevisiae protein Otu1.Otu1 has been demonstrated to bind Cdc48p and degrade polyubiquitin chains. 产品介绍 Human Yod1 recombinant protein, with His-tag, expressed in E. coli.
询价背景介绍 USP51, a member of the USP family of cysteine proteases, contains a UBP-type Zn-finger and is expressed in the prostate, brain lung, aorta, and kidney. 产品介绍 Human USP51 recombinant protein (Genbank Accession No. Q70EK9), with N-terminal SUMO- and His-tags, expressed in E. coli.
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