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产品介绍 Human CD46-BC, also known as membrane co-factor protein, Genbank Accession No. BC_030594, a.a. 35-328 with C-terminal His-tag, expressed in a HEK293 cell expression system. MW = 36.6 kDa (precursor), 34.2 kDa (mature). Note: this protein is expressed with a 34 amino acid signal sequence that is cleaved after secretion and is heavily glycosylated, resulting in a protein that runs at a higher apparent MW.
询价产品介绍 Human secreted LAG3, also known as Lymphocyte-Activation Gene 3 and CD223. GenBank Accession No. NM 002286, a.a. 23-450 expressed in a HEK293 cell expression system with C-terminal His-Tag. MW = 48 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
询价产品介绍 Human DRAK2, also known as DAP kinase-related apoptosis-inducing protein kinase 2 or death-associated protein kinase-related 2 (GenBank Accession No. NM_004226.3), a.a. 2-372 (end), MW = 43 kDa, expressed in a baculovirus-infected Sf9 cell expression system.
询价产品介绍 Human DRAK2, (GenBank Accession No. NM_004226.3), a.a. 2-372 (end), with N-terminal GST-tag, MW = 69 kDa, expressed in a baculovirus-infected Sf9 cell expression system.
询价产品介绍 Purified, recombinant, humanized Anti-β-amyloid (IgG1) antibody, expressed in HEK293 cells. This antibody reacts with human β-amyloid and has not been tested for cross-reactivity with other species.
询价背景介绍 The low density lipoprotein receptor (LDLR protein) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. In case of HIV-1 infection, it functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR protein, inducing LDLR degradation. 产品介绍 Mouse low density lipoprotein receptor (LDLR), also known as FH, FHC, and LDLCQ2, GenBank Accession No. NM_010700, a.a. 22-790, with C-terminal Flag-tag, MW=87 kDa87, expressed in a HEK293 cell expression system. *Note: LDLR is heavily glycosylated, resulting in higher molecular weight.
询价产品介绍 Neutralizing recombinant human antibody recognizing the Lag-3 binding region.
询价产品介绍 Recombinant human TIGIT inhibitor antibody recognizing an epitope that prevents TIGIT interaction with CD155 on immune cells.
询价产品介绍 Purified recombinant human anti-PCSK9 (IgG4) antibody with a C-terminal Avi-tag, expressed in HEK293 cells. Purified antibody was enzymatically biotinylated using AviTag™ technology. This protein reacts with human PCSK9 and has not been tested for cross-reactivity with other species.
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