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产品介绍 Human Arginase 2B (ARG2B) protein, also known as LCN7 and LIECF3, GenBank Accession No. NM_001172, amino acids 22-355, with an N-terminal His-tag, expressed in an SF9 insect cell expression system. MW = 38 kDa.
询价产品介绍 Human Arginase 1 (ARG1) protein, also known as LCN7 and LIECF3, GenBank Accession No. NM_000045, amino acids 1-322, with a C-terminal His-tag, expressed in an HEK293 cell expression system. MW = 36 kDa.
询价产品介绍 Human BACE1, also known as beta-site amyloid precursor protein cleaving enzyme 1 and ASP2, GenBank Accession No. NM_012104.4, a.a. 22-460, with C-terminal His-Tag, MW=50 kDa, expressed in HEK293 cells.
询价产品介绍 Bace1 (β-secretase 1) is an aspartic protease that is involved in the processing of the Amyloid precursor protein (APP). Cleavage of APP by BACE1 followed by γ-secretase results in β-amyloid peptide production, which ultimately leads toxic Aβ accumulation. In Alzheimer's disease (AD), it has been widely accepted that Aβ aggregation plays a critical role in AD pathogenesis, suggesting that BACE1 could be a potential target to treat AD. The BACE1 FRET Assay Kit is designed to measure BACE1 activity for screening and profiling applications based on fluorescence resonance energy transfer (FRET) using a labeled peptide substrate (below).
询价产品介绍 Fc region of human immunoglobulin G4 (IgG4) protein, a.a. 99-327, Genbank Accession #P01861, expressed in an HEK293 cell expression system. MW = 27 kDa.
询价产品介绍 Fc region of human immunoglobulin G1 (IgG1) protein, also known as Il-4, GenBank Accession No. P01857, a.a. 100-330, expressed in an HEK293 cell expression system. MW = 27 kDa.
询价背景介绍 Methionine Adenosyltransferase 2A (MAT2A), also known as AdoMet Synthase 2, catalyzes the formation of S-adenosylmethionine from methionine and ATP. It is an important enzyme in cellular metabolism and is expressed in extrahepatic tissues. In liver, MAT2a expression is associated with growth, dedifferentiation, and cancer. 产品介绍 The MAT2a Inhibitor Screening Assay Kit is designed to measure MAT2A activity for screening and profiling applications. The MAT2A assay kit comes in a convenient 384-well format, with purified recombinant MAT2A enzyme, L-Methionine, ATP, MAT2A assay buffer, and Colorimetric detection reagent for 384 enzyme reactions.
询价产品介绍 Human Anti-TIGIT neutralizing antibody recognizing the TIGIT binding region on immune cells.
询价背景介绍 This antibody binds and blocks the activation of the PD-1 receptor. The antibody is humanized, containing a human IgG4 Fc region with an engineered hinge region mutation (S228P) designed to prevent the exchange of IgG4 molecules. This antibody is equivalent to Nivolumab, which has been approved by the FDA for the treatment of melanoma and metastatic squamous non-small cell lung cancer. 产品介绍 Humanized recombinant anti-PD-1 (IgG4) antibody with S228P mutation, expressed in HEK293 cells. This antibody has not been tested with other species.
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