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产品介绍 Mouse OX40L, also known as tumor necrosis factor ligand superfamily member 4, TNFSF4, and CD252, GenBank Accession No. NM_009452, a.a. 49-198 (end) with an N-terminal His-tag, expressed in a HEK293 cell expression system. MW = 18 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
询价产品介绍 Human TIM-4, also known as T-cell immunoglobulin and mucin domain containing 4, TIMD-4, and T-cell membrane protein 4 with a C-terminal Avi-His-Tag. GenBank Accession No. NM_138379, a.a. 25-315 expressed in a HEK293 cell expression system. MW = 35 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
询价产品介绍 Human TIM-1, also known as T-cell immunoglobulin, Hepatitis A virus cellular receptor 1, and HAVCR1, with a C-terminal Avi-His-Tag. GenBank Accession No. NM_012206, a.a. 21-293, expressed in a HEK293 cell expression system. MW = 32 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
询价产品介绍 Human secreted CD113, also known as Poliovirus receptor-related 3, PVRL3, and nectin-3, GenBank Accession No. NM_015480.2, a.a. 58-400 expressed in a HEK293 cell expression system, with C-terminal Fc-Fusion-Avi-tag. MW = 66 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
询价产品介绍 Human CD48, Fc fusion protein, also known as Cluster of Differentiation 48, BLAST-1, or SLAMF2. GenBank Accession No. NM_001778, a.a. 27-220 expressed in a HEK293 cell expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 using Avi-tag™ technology. MW = 51 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
询价产品介绍 Human CD244, Fc fusion protein, also known as Natural Killer Cell Receptor 2B4. GenBank Accession No. NM_016382, a.a. 22-229 expressed in a HEK293 cell expression system. This protein is fused at the C-terminus to the Fc region of human IgG1. MW = 52 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
询价产品介绍 Human CD150, Fc fusion protein, also known as signaling lymphocytic activation molecule (SLAM) or SLAMF1. GenBank Accession No. NM_003037, a.a. 21-237 expressed in a HEK293 cell expression system. This protein is fused at the C-terminus to the Fc region of human IgG1. MW = 53 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
询价产品介绍 The CTLA4:B7-1 TR-FRET Assay is designed to measure the inhibition of CTLA4 binding to B7-1 in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; a sample containing biotinylated CTLA4, B7-1 protein, anti-His Tb donor, dye-labeled acceptor, and an inhibitor is incubated for two hours. Then, the fluorescence intensity is measured using a fluorescence reader.
询价背景介绍 The activation of naive T cells requires two signals; the specific T cell receptor recognition of MHC/Antigen on the surface of the antigen-presenting cell (APC), and the binding of B7-2 (CD86) ligand on the APC with the CD28 receptor on the T cell surface. CD28:B7-2 interaction is an important drug target for the regulation of T cells involved in autoimmunity, inflammation, tumor recognition, and immune tolerance. 产品介绍 The CD28:B7-2[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CD28:B7-2 signaling. The key to this kit is the high sensitivity of detection of biotin-labeled B7-2 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, CD28 is coated on a 96-well plate. Next, B7-2 is incubated with CD28 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can be measured using a chemiluminescence reader.
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