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背景介绍 3-Deazaneplanocin A (DZNep) is an S-Adenosylhomocysteine Hydrolase inhibitor and histone methyltransferase EZH2 inhibitor. It switches on repressed tumor suppressor genes and induces apoptosis by inhibiting the expression of EZH2. Blocks EZH2 activity and trimethylation of lysine 27 on histone H3 in vitro. Induces apoptotic cell death in cancer cells and inhibits s-adenosylhomocysteine (SAH) hydrolase. Decreases global DNA methylation and enhances Oct 4 expression in chemically induced pluripotent stem cells (CiPSCs). DZNeP decreased cell migration, which was additionally reduced by DZNeP/gemcitabine combination. 产品介绍 Cell-permeable inhibitor of the histone methyltransferase EZH2.
询价背景介绍 3-Deazaneplanocin A (DZNep) is an S-Adenosylhomocysteine Hydrolase inhibitor and histone methyltransferase EZH2 inhibitor. It switches on repressed tumor suppressor genes and induces apoptosis by inhibiting the expression of EZH2. Blocks EZH2 activity and trimethylation of lysine 27 on histone H3 in vitro. Induces apoptotic cell death in cancer cells and inhibits s-adenosylhomocysteine (SAH) hydrolase. Decreases global DNA methylation and enhances Oct 4 expression in chemically induced pluripotent stem cells (CiPSCs). DZNeP decreased cell migration, which was additionally reduced by DZNeP/gemcitabine combination. 产品介绍 Cell-permeable inhibitor of the histone methyltransferase EZH2.
询价背景介绍 CUDC-907 has a long half-life in murine tumors. CUDC-907 induces apoptosis and inhibits cancer cell proliferation in xenograft tumors. 产品介绍 CUDC-907 is a dual PI3K and HDAC inhibitor
询价背景介绍 CUDC-907 has a long half-life in murine tumors. CUDC-907 induces apoptosis and inhibits cancer cell proliferation in xenograft tumors. 产品介绍 CUDC-907 is a dual PI3K and HDAC inhibitor
询价背景介绍 CUDC-907 has a long half-life in murine tumors. CUDC-907 induces apoptosis and inhibits cancer cell proliferation in xenograft tumors. 产品介绍 CUDC-907 is a dual PI3K and HDAC inhibitor
询价产品介绍 Hydrochloride salt of CHIR 99021, a highly selective glycogen synthase kinase-3 (GSK-3) inhibitor that can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β).
询价产品介绍 Hydrochloride salt of CHIR 99021, a highly selective glycogen synthase kinase-3 (GSK-3) inhibitor that can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β).
询价产品介绍 CHIR-99021 is a highly specific glycogen synthase kinase-3 (GSK-3) inhibitor that can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β).
询价产品介绍 CHIR-99021 is a highly specific glycogen synthase kinase-3 (GSK-3) inhibitor that can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β).
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