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产品介绍 Human Sphingosine kinase 1 or SphK1 (GenBank Accession No. AF200328), full length with N-terminal His-tag, MW=46.9 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
询价产品介绍 Human recombinant RB protein (773-end) with N-terminal GST-tag (GenBank Accession No. NM_000321), MW=43.5 kDa, expressed in an E. coli expression system.
询价背景介绍 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. 产品介绍 Human FKBP12 (FK506 binding protein 1A, transcript variant 12A), GenBank Accession No. NM_054014, full length with N-terminal His-tag, MW= 13.1 kDa, expressed in an E. coli expression system. 5References: 1. Knappe,T.A. et al., J. Mol. Biol. 368 (5), 1458-1468 (2007). 2. Wear,M.A. et al., Protein Expr. Purif. 51 (1), 80-95 (2007).
询价背景介绍 MBP is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. MBP is also present in the bone marrow and the immune system. Differential splicing events combined with post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. MBP is commonly used as a substrate for many kinases and methyltransferases. 产品介绍 Human myelin basic protein (MBP), GenBank Accession No. NM_001025101, a.a. 2-304(end), with N-terminal His-tag, MW=34 kDa, expressed in an E. coli cell expression system.
询价背景介绍 BRAF is a member of the RAF family that is activated by members of the Ras family upon growth factor-induced stimulation. Active Ras can induce heterodimerization of cRaf and BRAF and this may explain the observed cooperativity of cRaf and BRaf in cells responding to growth factor signals (1). Activating mutations in the BRAF gene are present in a large percentage of human malignant melanomas and in a proportion of colon cancers. The vast majority of these mutations result in a valine to glutamic acid change at residue 599 within the activation segment of B-RAF (2). 产品介绍 Human v-raf murine sarcoma viral oncogene homolog B1 (BRAF), GenBank Accession No. NM_004333, a.a. 417-end with Val-to-Glu mutation on a.a. 600* and N-terminal GST-tag and His-tag, MW=69 kDa, expressed in Sf9 insect cells via a baculovirus expression system.*This mutation is often cited as V600E.
询价产品介绍 Human MEK1, or mitogen-activated protein kinase kinase 1 (MAP2K1) (GenBank Accession No. NM_002755), full length a.a. 2 - 393 (end), with N-terminal GST-tag, MW = 69 kDa, expressed in baculovirus-infected Sf9 cell expression system.
询价产品介绍 Human eIF4e (eukaryotic translation initiation factor 4E) (GenBank Accession No. NM_001968), a.a. 2-216 with N-terminal GST-tag, MW= 51 kDa, expressed in an E. coli expression system.
询价产品介绍 Human recombinant Cofilin1 (GenBank Accession No. NM_005507), a.a. 2-end with N-terminal GST-tag, MW= 44 kDa, expressed in an E. coli expression system.
询价产品介绍 Human ATF2 (GenBank Accession No. NM_001880), a.a. 19 - 96 with N-terminal GST-tag, MW= 34.8 kDa, expressed in an E. coli expression system.
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