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产品介绍 The DNMT3A Direct Activity Assay Kit is designed to measure DNMT3A activity for screening and profiling applications. The key to the DNMT3A Direct Activity Assay Kit is a highly specific antibody that recognizes 5-methylcytosine of the substrate. With this kit, only three simple steps on a microtiter plate are required for detection of DNMT3A activity. First, S-adenosylmethionine is incubated with a sample containing assay buffer and DNMT3A/3L for two hours. Next, primary antibody is added. Finally, the plate is treated with an HRP-labeled secondary antibody followed by addition of the HRP substrate to produce chemiluminescence that can then be measured using a chemiluminescence reader.
询价背景介绍 S-Adenosyl-L-homocysteine is an amino acid derivative used in several metabolic pathways in most organisms. S-Adenosyl-L-homocysteine (SAH) is an amino acid derivative and an intermediate, by-product, or modulator of several metabolic pathways, including the activated methyl cycle and cysteine biosynthesis. SAH is formed by the demethylation of S-adenosyl-L-methionine. It is also a product of S-adenosyl-methionine (SAM)-dependent methylation of biological molecules, including DNA, RNA, and histones and other proteins. Inhibitors that block its hydrolysis are being developed as anti-viral, anti-parasitic, anti-arthritic and immunosuppressive agents. 产品介绍 S-(5'-Adenosyl)-L-homocysteine (AdoHCys, SAH) is a competitive inhibitor (versus AdoMet) of DNA methyltransferases. AdoHcy is used in a variety of studies on epigenetics in hyperhomocysteinemic states. EC Number: 213-560-8
询价背景介绍 Adenosyl Homocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependant methyl transferase reactions and therefore may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. 产品介绍 Rabbit polyclonal to Adenosyl Homocysteine Purity: IgG fraction Tested Applications: ELISA (competitive): 1:2500 (final dilution), ELISA (hap-BSA, EPT): 1:24000. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Cellular localization: Cytoplasmic
询价产品介绍 5X mixture of full length human Histones H2A (GenBank Accession No. NM_033445), and H2B (NM_003528), each with N-terminal His-tag, expressed in E. coli. MW=14.8 kDa (H2A), 14.6 kDa (H2B).
询价产品介绍 Human Histone 4 (HIST2H4A) (GenBank Accession No. NM_003548), a.a. 2-103(end) with N-terminal His-tag, MW = 12.1 kDa, expressed in an E. coli expression system.
询价产品介绍 Human Histone 3 (HIST1H3E), GenBank Accession No. NM_003532, a.a. 2-136(end) with N-terminal His-tag MW = 15.4 kDa, expressed in an E. coli expression system.
询价产品介绍 Human Histone 2B, GenBank Accession No. NM_003528, a.a. 2-126(end) with N-terminal His-tag, MW = 14.6 kDa, expressed in an E. coli expression system.
询价产品介绍 Human Histone 2A, GenBank Accession No. NM_033445, a.a. 2-130(end) with N-terminal His-tag, MW = 14.8 kDa, expressed in an E. coli expression system.
询价产品介绍 Human Histone 4 (HIST2H4A) (GenBank Accession No. NM_003548), a.a. 2-103(end) with N-terminal His-tag, MW = 12.1 kDa, expressed in an E. coli expression system.
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