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背景介绍 Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histones play a central role in the regulation of transcription, DNA repair, DNA replication and chromosomal stability. These different functions are established via a complex set of post-translational modifications which either directly or indirectly alter chromatin structure and DNA accessibility to facilitate transcriptional activation or repression or other nuclear processes. 产品介绍 Polyclonal antibody raised in rabbit against histone H4 using a KLH-conjugated synthetic peptide containing an unmodified sequence from the central part of the protein.
询价背景介绍 Phosphorylation of H3S10 is associated with mitosis 产品介绍 Polyclonal antibody raised in rabbit against histone H3 containing the phosphorylated serine 10 (H3S10p), using a KLH-conjugated synthetic peptide.
询价产品介绍 Polyclonal antibody raised in rabbit against the region of histone H3 containing the asymmetrically dimethylated R17 and the acetylated lysine 18 (H3R17me2(asym)K18ac), using a KLH-conjugated synthetic peptide.
询价产品介绍 Polyclonal antibody raised in rabbit against histone H3 containing the asymmetrically dimethylated arginine 17 (H3R17me2(asym)), using a KLH-conjugated synthetic peptide.
询价背景介绍 Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. 产品介绍 Monoclonal antibody raised in mouse against a region of histone H3 containing the unmodified lysine 9 (H3K9un), using a KLH-conjugated synthetic peptide
询价产品介绍 Polyclonal antibody raised in rabbit against histone H3 containing trimethylated lysine 9 and the phosphorylated serine 10 (H3K9me3S10p), using a KLH-conjugated synthetic peptide.
询价背景介绍 Trimethylation of histone H3K9 is associated with satellite repeat regions and ZNF repeat genes, and correlates with gene repression. 产品介绍 Polyclonal antibody raised in rabbit against the region of histone H3 containing the trimethylated lysine 9 (H3K9me3), using a KLH-conjugated synthetic peptide
询价背景介绍 Trimethylation of histone H3K9 is associated with satellite repeat regions and ZNF repeat genes, and correlates with gene repression. 产品介绍 Monoclonal antibody raised in mouse against histone H3 trimethylated at lysine 9 (H3K9me3), using a KLH-conjugated synthetic peptide.
询价背景介绍 Dimethylation of histone H3K9 is more frequently found in silent genes. 产品介绍 Polyclonal antibody raised in rabbit against the region of histone H3 containing the dimethylated lysine 9 (H3K9me2), using a KLH-conjugated synthetic peptide
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