服务平台拥有丰富的技术服务经验，一流的仪器设备，先进的检测手段和严格的质量控制体系，力求为全球药物研发机构提供优质高效的技术服务
磷脂酰肌醇(PI) 及其磷酸化衍生物， 统称为磷酸肌醇(Phosphoinositides)，是重要的第二信使，而第二信使作为信号分子在细胞膜重构中起关键作用。它们由一类被称为磷酸肌醇脂质激酶(Phosphoinositide Lipid Kinases, PIKs) 的激酶家族催化产生。在哺乳动物中，已确定19 个PIK 亚型。根据其对磷酸化肌醇环第 3、4、5位羟基基团磷酸化偏好，大致分为三个主要的家族：磷酸肌醇3- 激酶(PI3Ks)，磷脂酰肌醇4- 激酶(PI4Ks) 和磷酸肌醇磷酸- 激酶(PIP5Ks和 PIP4Ks)。
询价PIM2 Kinase Enzyme System Easily Screen and Profile PIM2 Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价PIM2 Kinase Enzyme System Easily Screen and Profile PIM2 Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价PIM1 Kinase Enzyme System Easily Screen and Profile PIM1 Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价PIM1 Kinase Enzyme System Easily Screen and Profile PIM1 Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价Kinase Fusion Vector for NanoBRET™ Target Engagement Transfection-ready DNA to express full-length PIKFYVE kinase fused to NanoLuc® Luciferase Measures kinase target engagement in live cells Use with NanoBRET™ TE Intracellular Kinase Assay, Adherent Format protocol
询价Regulatory Vector for NanoBRET™ Target Engagement Transfection-ready DNA to express full-length PIK3R1 regulatory protein Use with select kinase-NanoLuc® fusion vectors and NanoBRET™ TE Intracellular Kinase Assay
询价Kinase Fusion Vector for NanoBRET™ Target Engagement Transfection-ready DNA to express full-length PIK3C3 kinase fused to NanoLuc® Luciferase Measures kinase target engagement in live cells Use with NanoBRET™ TE Intracellular Kinase Assay, Adherent Format protocol
询价Lipid Kinase Assays: PI3K-Glo™ Class I Profiling Kit Simple, Add-and-Read Assay to Detect Class I PI3K Activity Includes purified recombinant proteins of class I PI3Ks, optimized reaction buffer, ready-to-use lipid kinase substrates and ADP-Glo™ Kinase Assay High signal-to-background ratios even at low percent substrate conversion Easily scalable to 1,536-well format
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