服务平台拥有丰富的技术服务经验，一流的仪器设备，先进的检测手段和严格的质量控制体系，力求为全球药物研发机构提供优质高效的技术服务
CDC7/DBF4 Kinase Enzyme System Easily Screen and Profile CDC7/DBF4 Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价CD40 Bioassay是一种基于细胞的生物发光检测方法，可测定配体或激动剂抗体以及其他可结合并激活CD40的生物大分子药物的药效和稳定性。CD40在B细胞、树突状细胞和单核细胞的表面表达，是肿瘤坏死因子受体超家族的一员。CD40配体（CD154）是CD40的主要配体，由活化的T细胞（细胞免疫和体液免疫的关键调节体）表达。通过CD40发出的信号可触发抗原呈递细胞的活化。 CD40激动剂抗体可模仿CD40配体，能够在T细胞介导免疫的小鼠模型中替代CD4+辅助型T细胞。因此，CD40激动剂抗体可以挽救抗原呈递细胞在荷瘤宿主中的功能并恢复针对肿瘤抗原的有效免疫应答。通过多个临床前模型得到的后续数据表明，将CD40激动剂与细胞毒素类药物联合使用可以产生协同增效作用，特别是在化学疗法中。 FcγRIIb CHO-K1细胞经过工程改造可表达人FcγRIIb。以细胞传代模型（CPM）形式提供这类细胞，其中包含的冻存细胞可被复苏、繁殖和建立细胞库以便长期使用。这些不是含有报告基因的细胞，仅起交联抗CD40、抗OX40、抗4-1BB或抗GITR抗体的作用。
询价Measure Potency and Stability of Biologics Designed to Block CD28 Interactions，96- and 384-well plate compatible，Prequalified according to ICH guidelines，No primary cell culture required，Available in convenient thaw-and-use format
询价Measure Potency and Stability of Biologics Designed to Activate CD28，96- and 384-well plate compatible，Prequalified according to ICH guidelines，No primary cell culture required，Available in convenient thaw-and-use format
询价Regulatory Vector for NanoBRET™ Target Engagement Transfection-ready DNA to express full-length CCNY regulatory protein Use with select kinase-NanoLuc® fusion vectors and NanoBRET™ TE Intracellular Kinase Assay
询价Regulatory Vector for NanoBRET™ Target Engagement Transfection-ready DNA to express full-length CCNT1 regulatory protein Use with select kinase-NanoLuc® fusion vectors and NanoBRET™ TE Intracellular Kinase Assay
询价Regulatory Vector for NanoBRET™ Target Engagement Transfection-ready DNA to express full-length CCNL2 regulatory protein Use with select kinase-NanoLuc® fusion vectors and NanoBRET™ TE Intracellular Kinase Assay
询价Regulatory Vector for NanoBRET™ Target Engagement Transfection-ready DNA to express full-length CCNK regulatory protein Use with select kinase-NanoLuc® fusion vectors and NanoBRET™ TE Intracellular Kinase Assay
询价Regulatory Vector for NanoBRET™ Target Engagement Transfection-ready DNA to express full-length CCNH regulatory protein Use with select kinase-NanoLuc® fusion vectors and NanoBRET™ TE Intracellular Kinase Assay
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