核受体筛选服务

核受体属于大的转录因子超家族,在多细胞生物体的发展和稳态方面发挥着重要的调节作用。比如控制胚胎发育、器官生理、细胞分化、稳态等重要的生理功能。除了发挥这些正常的生理功能之外，核受体涉及到许多病理过程,如癌症、糖尿病、类风湿关节炎、哮喘或激素抵抗综合征。在生物医学研究中,这些转录调节的重要性是难以低估。

盛祺兆生物能够为客户提供优质全面的核受体筛选服务，可提供96孔和384孔两种板型的筛选模式，加速您的药物研发进程。

核受体筛选服务，可提供96孔和384孔两种板型的筛选模式，检测方式用的是TR-FRET（共振能量转移），需要注意的是每种核受体会对应多种亚型，比如ERR这个受体（雌激素相关受体）就有3种不同亚型，对于有多种亚型的靶点必须要确定知道自己要做的是哪种亚型。

Target	Assay	Format
Androgen Receptor	TR-FRET/Cell based	96/384
Aryl Hydrocarbon Receptor	Cell based	96/384
Constitutive Androstane Receptor isoform 1/3	TR-FRET/Cell based	96/384
ER alpha/beta	TR-FRET/Cell based	96/384
ERR (estrogen related receptor) alpha/beta/gamma	TR-FRET/Cell based	96/384
FXR (farnesoid X receptor)	TR-FRET	96/384
Glucocorticoid Receptor (GR)	TR-FRET/Cell based	96/384
Liver Receptor Homolog-1	Cell based	96/384
LXR (liver X receptor) alpha/beta	TR-FRET/Cell based	96/384
Mineralocorticoid Receptor (MR)	Cell based	96/384
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2)	Cell based	96/384
PPAR alpha/delta/gamma	TR-FRET/Cell based	96/384
Pregnane X Receptor	Cell based	96/384
Progesterone Receptor	TR-FRET/Cell based	96/384
RAR-related orphan receptor gamma (RORγ)	Cell based	96/384
Retinoic Acid Receptor (RAR) alpha/beta/gamma	TR-FRET/Cell based	96/384
Retinoid X Receptor (RXR) alpha/beta/gamma	TR-FRET/Cell based	96/384