服务平台拥有丰富的技术服务经验，一流的仪器设备，先进的检测手段和严格的质量控制体系，力求为全球药物研发机构提供优质高效的技术服务
发布日期：2024-09-29
Inflammatory cytokines, released during infection or disease, recruit and activate immune cells, induce acute-phase proteins, and trigger systemic responses like fever. However, excessive production of these cytokines can cause chronic inflammation, tissue damage, and autoimmune diseases. Understanding their clinical significance has led to targeted therapies that block their activity, offering new treatment options for inflammatory diseases.
Cytokine-responsive Cell Lines: IL-4, IL-6, IL-13, IL-15, IL-23, IL-27
The discovery of new biologics can be greatly facilitated by luciferase reporter cell lines, which respond to cytokine stimulation with increased luciferase activity.
Sensitive and high signal-to-noise ratio with up to 200-fold induction
Quantitative: Reliable EC50 and IC50 determination
Validated, protocols provided for key experiments
